Endocrine Abstracts

Introduction: Primary hyperaldosteronism is the first cause of secondary hypertension during pregnancy. The diagnosis is too difficult due to the changes in the renin angiotensin system.Observation: We report the case of a 37 years old women with a history of pre-eclampsia during her pregnancy who consulted the emergency 20 days after delivery for severe hypertension (23/11) and severe hypokalemia (2.2 mmol/l ) resistant to intravenous treatment. The ald...

Introduction: The pituitary adenoma is the most frequent begnin pituitary tumor. They are labeled based on their size, tumors smaller than 1 cm called microadenomas and tumors bigger than 1 cm called macroadenomas. Moreover, they can be functional or non functional. Among the functional ones, gonadotroph adenomas represent 15 to 20%.ObservationWe report the case of a 27 years old women, who consulted for secondary amenorrhea for 1 ...

Introduction: Cardiothyreosis or thyrotoxic heart disease is the most dangerous complication of hyperthyroidism. This rare complication can be revealing and occurs mostly to fragile patients ; eldery or individuals with preexisting cardiac troubles.Observation: We report the case of a 59 years old male without medical history, who consulted the emergency for dyspnea and palpitations due to atrial fibrillation ( ACFA ) not well tolerated with both respira...

Introduction: Graves’ ophthalmopathy (GO) is an autoimmune disorder affecting the retro-orbital tissues. It represents the main extra- thyroidal expression of Graves’ disease (GD). In children, GO is less common and less severe than in adults. Herein we report a case of GO in a child.Case report: An 11-year-old girl with family history of autoimmune thyroid disease was referred to our department for evaluation of suspected hyperthyroidism. She ...

Introduction: The coexistence of two types of tumors of different origins in the same thyroid is a rare phenomenon. Its etiopathogenesis remains unknown. We report the case of a mixed papillary and medullary carcinoma of the thyroid revealed by a compressive goiter.Case report: A 70-year old woman with a history of right lobo-isthmusectomy for a toxic solitary adenoma, presented 30 years later with a chief complaint of a cervical mass accompanied by diff...

Introduction: Primary hyperparathyroidism (PHP) is the result of excessive, independent, and inappropriate production of parathyroid hormone (PTH). The aim of this work is to study the epidemiological, clinico-biological and therapeutic aspects of PHP.Materials and methods: This is a retrospective study of 34 patients hospitalized for the management of PHP in the Endocrinology Department of the Military Hospital of Tunis between March 1999 and July 2018....

Introduction: The ectopic posterior pituitary is a rare condition which is characterized by the ectopic location of posterior lobe of pituitary, pituitary stalk abnormalities, and associated clinical manifestations of anterior lobe related growth hormone dysfunction or less commonly multiple anterior pituitary dysfunctions. We describe the case of a young female who presented with short stature and was found to have ectopic posterior pituitary.Case prese...

Background: Multiple endocrine neoplasia (MEN) are rare and are characterized by the association of a neoplasia or hyperplasia of at least two endocrine glands. Rare cases of atypical MEN were reported in the literature. We describe a rare combination of acromegaly, papillairy thyroid carcinoma and primary hyperaldosteronism.Case presentation: We report a case of a 48-year old woman operated for papillary thyroid carcinoma. Five years later, sh...

Introduction: Androgenic insensitivity syndrome (AIS) is an X-linked genetic disease characterized by resistance to the actions of androgen in an individual with 46, XY karyotype. It is the most common cause of DSD in 46, XY individuals.Case report: We report a case of a 16-year-old girl who consulted for primary amenorrhea and hirsutism. Our patient had a 9-year-old sister who was operated for an inguinal hernia and the anathomopathological study conclu...

Background: The primary empty sella (PES) is radiologically defined as partial when less than 50% of the sella is filled with cerebrospinal fluid (CSF) and pituitary gland thickness is ≥3 mm or total when more than 50% of the sella is filled with CSF and the gland thickness is ≤2 mm in diameter.The aim of our study was to evaluate clinical and radiological aspects of PES.Methods: We retrospectively evaluated clinical features and radiological...